岐阜市立女子短期大学研究紀要第55輯（平成18年3月）
抄録
活性酸素によるマウスのリンパ球アポトーシスに及ぼすビタミンB6
の影響
Study on Apoptosis (6)
Effect of vitamin B6 on active oxygen - induced apoptosis in lymphocyte.
| 道家晶子 |
| Shoko DOKE |
Abstract
The mechanism of active oxygen induced - apoptosis in lymphocyte by vitamin B6 as compared with those by vitamin C was studied. The protective effect of vitamin B6 was dependent on concentration and occurred only in the millimolar concentration range. In contrast, vitamin C did not show the dependent on concentration. Oxidative stress activates apoptosis and antioxidants protect against apoptosis in vitro. These results suggest that vitamin B6 may have an important role in the induction of oxygen-induced apoptosis.
Key words : apoptosis lymphocyte vitamin B6